The Qur'an is significantly different than the Torah, Psalms, and Gospels in many respects.
One particularly important difference between the Qur'an and Bible is found in Sura 4:157-158:
"And for claiming that they killed the Messiah, Jesus, son of Mary, the messenger of GOD. In fact, they never killed him, they never crucified him - they were made to think that they did. All factions who are disputing in this matter are full of doubt concerning this issue. They possess no knowledge; they only conjecture. For certain, they never killed him."
This of course directly contradicts the four Gospel accounts, which all declare that Jesus was crucified and resurrected. The Qur'an also holds in 37:102 that Ishmael, rather than Isaac, was the son which Abraham was commanded to sacrifice to test his faith. The Qur'an also contains many major differences from the Bible in its creation account. The Koran vs. Genesis
Through his vision, Muhammad wrote many things that do not measure up to the Bible. In particular he contradicts three fundamental doctrines of Christianity. These three Christian fundamentals are; salvation and how to achieve it, who Jesus really is, and the birth of Jesus. We will lay out what the Bible says and what the Qur’an says on those topics, citing several passages from each book but taking the Bible as true.
As an introduction to this article, let us explain who Muhammad and Allah were, are and how they are viewed by Muslims.
Muhammad, born in 570 AD, is said to be the last prophet of mankind. Early Muslim reports dating around 610-611 AD say that, while meditating in a cave near Mecca, Muhammad experienced a vision of the angel Gabriel who came commanding him to recite and memorize verses that he later wrote down and collected. By 613 he had taken this message to the public. Most Muslims consider him to be the creator of Islam.
Allah is the Arabic word for God. From the point of view of traditional Islamic theology, Allah, 1 of the 99 other names, is the most precious one, as it is the name of God’s presence. Muslims believe that the name Allah had existed before the time of Adam, the first human. In Islam, there is only one God and Muhammad is the last messenger. Read that last sentence carefully as it will be brought up later. The fact that in Islam there is only one God completely contradicts the Biblical view of God.
The Bible throughout fully supports the idea of the Holy Trinity, God revealed as three persons, yet one God; the Father (God), the Son (Jesus Christ) and the Holy Spirit (who lives in the believer's heart). 1 John 5:7 "For there are three that bear record in heaven, the Father, the Word, and the Holy Ghost: and these three are one."
Having very briefly covered a little Islamic history, we turn to the first topic, salvation. According to the Bible, salvation is obtained only through faith in Jesus Christ, the son of God.
1 Thessalonians 5:9 "For God hath not appointed us to wrath, but to obtain salvation by our Lord Jesus Christ..."
Acts 4:12 “Salvation is found in no one else, for there is no other name under heaven given to men by which we must be saved.”
Romans 10:9 “...That if you confess with your mouth, ‘Jesus is Lord’ and believe in your heart that God raised him from the dead, you will be saved.”
Although God has prepared good works for us to walk in, salvation cannot be obtained by our own righteousness or good works:
Isaiah 64:6 "...all our righteousnesses are as filthy rags..."
Galatians 2:16 "...a man is not justified by the works of the law, but by the faith of Jesus Christ...by the works of the law shall no flesh be justified."
The Qur'an however says that through faith in Allah and good works only shall you enter paradise, or achieve salvation.
Sura 4:57 "But those who believe and do deeds of righteousness, We shall soon admit to Gardens, with rivers flowing beneath,- their eternal home: Therein shall they have companions pure and holy: We shall admit them to shades, cool and ever deepening."
Sura 65:10 "An Messenger, who rehearses to you the Signs of Allah containing clear explanations, that he may lead forth those who believe and do righteous deeds from the depths of Darkness into Light. And those who believe in Allah and work righteousness, He will admit to Gardens beneath which Rivers flow, to dwell therein for ever: Allah has indeed granted for them a most excellent Provision."
The second topic is who Jesus was. Does the Qur'an say He is really the Son of God as the Bible does?
John 10:30 "I and the Father are one."
Luke 1:30-33 "And the angel said to her, "The Holy Spirit will come upon you and the power of the Most High will overshadow you; therefore the child to be born will be called holy, the Son of God."
The Qur'an says that Jesus is no more than a servant to Allah and the Trinity is not to be talked about, since Allah is one God.
Sura 43:59-62 "He was no more than a servant: We granted Our favour to him, and We made him an example to the Children of Israel. And if it were Our Will, We could make angels from amongst you, succeeding each other on the earth. And (Jesus) shall be a Sign (for the coming of) the Hour (of Judgment): therefore have no doubt about the (Hour), but follow ye Me: this is a Straight Way. Let not the Evil One hinder you: for he is to you an enemy avowed."
Sura 4:171 "O People of the Book! Commit no excesses in your religion: Nor say of Allah aught but the truth. Christ Jesus the son of Mary was (no more than) a messenger of Allah, and His Word, which He bestowed on Mary, and a spirit proceeding from Him: so believe in Allah and His messengers. Say not "Trinity" : desist: it will be better for you: for Allah is one Allah: Glory be to Him: (far exalted is He) above having a son. To Him belong all things in the heavens and on earth. And enough is Allah as a Disposer of affairs."
Thirdly, the Bible clearly tells us that Jesus is the Son of God and a virgin gave birth to Him, He would bear the sins of this world to save mankind in fulfilment of earlier prophecies.
Luke 1:30-37 "And the angel said unto her, Fear not, Mary: for thou hast found favour with God. And, behold, thou shalt conceive in thy womb, and bring forth a son, and shalt call his name JESUS. He shall be great, and shall be called the Son of the Highest: and the Lord God shall give unto him the throne of his father David: And he shall reign over the house of Jacob for ever; and of his kingdom there shall be no end. Then said Mary unto the angel, How shall this be, seeing I know not a man? And the angel answered and said unto her, The Holy Ghost shall come upon thee, and the power of the Highest shall overshadow thee: therefore also that holy thing which shall be born of thee shall be called the Son of God. And, behold, thy cousin Elisabeth, she hath also conceived a son in her old age: and this is the sixth month with her, who was called barren. For with God nothing shall be impossible."
Matthew 1:18-25 "Now the birth of Jesus Christ was as follows: when His mother Mary had been betrothed to Joseph, before they came together she was found to be with child by the Holy Spirit. 19 And Joseph her husband, being a righteous man and not wanting to disgrace her, planned to send her away secretly. 20 But when he had considered this, behold, an angel of the Lord appeared to him in a dream, saying, "Joseph, son of David, do not be afraid to take Mary as your wife; for the Child who has been conceived in her is of the Holy Spirit. 21 "She will bear a Son; and you shall call His name Jesus, for He will save His people from their sins." 22 Now all this took place to fulfil what was spoken by the Lord through the prophet: 23 "BEHOLD , THE VIRGIN SHALL BE WITH CHILD AND SHALL BEAR A SON, AND THEY SHALL CALL HIS NAME IMMANUEL," which translated means, "GOD WITH US." 24 And Joseph awoke from his sleep and did as the angel of the Lord commanded him, and took Mary as his wife, 25 but kept her a virgin until she gave birth to a Son; and he called His name Jesus."
Luke 2:11-16 "The angel of the Lord said to the shepherds, "For to you is born this day in the city of David a Saviour, who is Christ the Lord. And this will be a sign for you: you will find a babe wrapped in swaddling cloths and lying in a manger." And suddenly there was with the angel a multitude of the heavenly host praising God and saying, "Glory to God in the highest, and on earth peace among men with whom he is pleased!" When the angels went away from them into heaven, the shepherds said to one another, "Let us go over to Bethlehem and see this thing that has happened, which the Lord has made known to us." And they went with haste, and found Mary and Joseph, and the babe (Jesus) lying in a manger."
The Qur'an states that Jesus is a baby who spoke to declare that He was a prophet sent from Allah not the Son of God. It almost describes it as not appropriate for Allah to father a prophet such as Jesus.
Sura 19:27-35 "At length she brought the (babe) to her people, carrying him (in her arms). They said: "O Mary! truly an amazing thing hast thou brought! "O sister of Aaron! Thy father was not a man of evil, nor thy mother a woman unchaste!" But she pointed to the babe. They said: "How can we talk to one who is a child in the cradle?" He said: "I am indeed a servant of Allah: He hath given me revelation and made me a prophet; "And He hath made me blessed wheresoever I be, and hath enjoined on me Prayer and Charity as long as I live; "(He) hath made me kind to my mother, and not overbearing or miserable; "So peace is on me the day I was born, the day that I die, and the day that I shall be raised up to life (again)"! Such (was) Jesus the son of Mary: (it is) a statement of truth, about which they (vainly) dispute. It is not befitting to (the majesty of) Allah that He should beget a son. Glory be to Him! when He determines a matter, He only says to it, "Be", and it is.
As you can hopefully and clearly see how the Qur'an teaches falsehoods about Jesus, you should begin to realise that the Qur'an is not the word of God, but stories to discredit the importance of Jesus. It is also important to note that in the Qur'an by saying that Jesus is no more than a prophet from Allah, he becomes no more than Muhammad, which is a human that Allah used to display a message. The danger in that is that Jesus was not a human, a servant or a prophet, HE IS GOD!
Muslims account for differences between Quranic versions and Biblical texts (both of which are considered divine by Muslims) by stating the Christian and Jewish texts have been corrupted and changed over time.
Bible-believers naturally reject this claim. They point to Sura 10:94, "If you have any doubt regarding what is revealed to you from your Lord, then ask those who read the previous scripture," as evidence that the Qur'an itself tells us to use the previous scriptures to validate its claims. They argue further that at the time that the Qur'an was written, according to the Qur'an, the Bible was not corrupt. But the Dead Sea Scrolls and the papyri fragments, which were written long before the time of Muhammad, have proved that our Bible has not been corrupted
Bible-believers also point out that the Qur'an, in fact, tells us that the Bible is not and cannot be corrupt and base their conclusion on the following verses:
"Rejected were the messengers before thee: with patience and constancy they bore their rejection and their wrongs, until Our aid did reach them: there is none that can alter the words (and decrees) of Allah. Already hast thou received some account of those messengers," (6:34).
"The word of thy Lord doth find its fulfillment in truth and in justice: None can change His words: for He is the one who heareth and knoweth all," (6:115).
"For them are glad tidings, in the life of the present and in the Hereafter; no change can there be in the words of Allah. This is indeed the supreme felicity," (10:64).
Muslims, however, believe that the earlier scriptures were inerrant in their original form, but become somewhat corrupted. They believe that while the earlier scriptures bear witness to the Truth of the Qur'an (as evidenced by the above verses), the Qur'an corrects and completes the corrupted earlier revelations of the Old and New Testaments.
What the Bible Says About the Qur'an

The Bible does not discuss the Qur'an directly, because it was completed over 500 years before the Qur'an was written. There is, therefore, a spectrum of views held by Christians on the Issue. However, many Bible believers apply Biblical warnings against antichrists and false prophets to the Qur'an. For instance:
1 John 2:22 - Who is a liar but he that denieth that Jesus is the Christ? He is antichrist, that denieth the Father and the Son."
1 John 4:1-3 - Beloved, believe not every spirit, but try the spirits whether they are of God: because many false prophets are gone out into the world. Hereby know ye the Spirit of God: Every spirit that confesseth that Jesus Christ is come in the flesh is of God: And every spirit that confesseth not that Jesus Christ is come in the flesh is not of God: and this is that [spirit] of antichrist, whereof ye have heard that it should come; and even now already is it in the world.
Matthew 7:15 - Beware of false prophets, which come to you in sheep's clothing, but inwardly they are ravening wolves.
Matthew 24:24 - For there shall arise false Christs, and false prophets, and shall shew great signs and wonders; insomuch that, if [it were] possible, they shall deceive the very elect.
Romans 10:9-10 - That if thou shalt confess with thy mouth the Lord Jesus, and shalt believe in thine heart that God hath raised him from the dead, thou shalt be saved. For with the heart man believeth unto righteousness; and with the mouth confession is made unto salvation.
Qur'anic difficulties
Those who view the Qur'an as false prophecy also point to a number of other verses to support their position:
It is okay to beat wives
"Men are the protectors and maintainers of women, because Allah has given the one more (strength) than the other, and because they support them from their means. Therefore the righteous women are devoutly obedient, and guard in (the husband's) absence what Allah would have them guard. As to those women on whose part ye fear disloyalty and ill-conduct, admonish them (first), (Next), refuse to share their beds, (And last) beat them (lightly); but if they return to obedience, seek not against them Means (of annoyance): For Allah is Most High, great (above you all)," (4:34).
In Paradise, voluptuous women await men for sensual gratification
"In them will be (Maidens), chaste, restraining their glances, whom no man or Jinn before them has touched," (55:56).
"We have created (their Companions) of special creation. And made them virgin - pure (and undefiled), - Beloved (by nature), equal in age,- For the Companions of the Right Hand," (56:35-38)
"Verily for the Righteous there will be a fulfillment of (the heart's) desires; Gardens enclosed, and grapevines, And voluptuous women of equal age," (78:31-33).
A boy and his dog sleep for 309 years in a cave.
"Such (being their state), we raised them up (from sleep), that they might question each other. Said one of them, "How long have ye stayed (here)?" They said, "We have stayed (perhaps) a day, or part of a day." (At length) they (all) said, "Allah (alone) knows best how long ye have stayed here...So they stayed in their Cave three hundred years, and (some) add nine (more)," (18:19,25).
The sun set in a pool of murky water
"Until, when he reached the setting of the sun, he found it set in a spring of murky water: Near it he found a People: We said: "O Zul-qarnain! (thou hast authority,) either to punish them, or to treat them with kindness." (18:86, Yusuf Ali, translation).
Jesus spoke while in the cradle
"But she pointed to the babe. They said: "How can we talk to one who is a child in the cradle?" He said: "I am indeed a servant of Allah: He hath given me revelation and made me a prophet," (19:29-30).
The Qur'an as a revelation of the same God to a different culture

Many see the Qur'an as a revelation of the same God to a different people, and believe that the inconsistencies and differences between the two pale in comparison to their similarities. They believe that while Christians, Jews, and Muslims obviously have many substantive differences, our shared struggle against atheism, secularism, and paganism is a much more pressing issue. They see Muhammed as analogous to Moses, bringing the law to a pagan people, and see the duty of Christians as bringing the message of Grace and Christ, which completes and corrects the message of the Qur'an.
In support of their position, they point to Jesus's words in Mark 9:38-41:
"Teacher," said John, "we saw a man driving out demons in your name and we told him to stop, because he was not one of us."
"Do not stop him," Jesus said. "No one who does a miracle in my name can in the next moment say anything bad about me, for whoever is not against us is for us. I tell you the truth, anyone who gives you a cup of water in my name because you belong to Christ will certainly not lose his reward.
As evidence that the Qur'an is not against Jesus, they point to the following verses from the Qur'an:
Those with Faith, those who are Jews, and the Christians and Sabaeans, all who have Faith in Allah and the Last Day and act rightly, will have their reward with their Lord. They will feel no fear and will know no sorrow. (Qur'an, Surat al-Baqara; 2:62)
Say, 'People of the Book! come to a proposition which is the same for us and you - that we should worship none but Allah and not associate any partners with Him and not take one another as lords besides Allah.' If they turn away, say, 'Bear witness that we are Muslims.'(Surah Al 'Imran; 3:64)
Today all good things have been made permissible for you. And the food of those given the Book is also halal for you and your food is halal for them. So are chaste women from among the muminun and chaste women of those given the Book before you, once you have given them their dowries in marriage, not in fornication or taking them as lovers. But as for anyone who rejects faith, his actions will come to nothing and in the akhira he will be among the losers. (Surat al-Ma'ida: 5:5)
Among the people of the Book there are some who have iman in Allah and in what has been sent down to you and what was sent down to them, and who are humble before Allah. They do not sell Allah's Signs for a paltry price. Such people will have their reward with their Lord. And Allah is swift at reckoning. (Surah Al 'Imran; 3:199)
Call to the way of your Lord with wisdom and fair admonition, and argue with them in the kindest way. Your Lord knows best who is misguided from His way. And He knows best who are guided. (Surat an-Nahl; 16:125)
...You will find the people most affectionate to those who have iman are those who say, 'We are Christians.' That is because some of them are priests and monks and because they are not arrogant. (Surat al-Ma'ida; 5:82)
Only argue with the People of the Book in the kindest way - except in the case of those of them who do wrong - saying, 'We have iman in what has been sent down to us and what was sent down to you. Our God and your God are one and we submit to Him.'(Surat al-'Ankabut; 29:46)
...There is a community among the People of the Book who are upright. They recite Allah's Signs throughout the night, and they prostrate. They have iman in Allah and the Last Day, and enjoin the right and forbid the wrong, and compete in doing good. They are among the salihun. You will not be denied the reward for any good thing you do. Allah knows those who have taqwa. (Surah Al 'Imran: 3:113-115)
Related References

Religion References (Bible vs. Qur'an)
All About Religion
All About Religion - Origin of Islam
All About Religion - Christianity
Handbook of Today's Religions by Josh McDowell
Handbook of Today's Religions - Islam
Handbook of Today's Religions - Christianity
Pro Bible References (Bible vs. Qur'an)
Christian Apologetics Research Ministry - Islam
Christian Answers - Islam
Answers in Genesis - Koran vs. Bible
Pro Qur'an References (Bible vs. Qur'an)
The Bible led me to Islam
Christ in Islam